Sixteen of the twenty-four teams that made it to Egypt continue with the dream of becoming champions after completion of the group stages.
The top two finishers of the six groups and the four best third place teams made up the line-up for the last 16.
Host Egypt topped group A with nine points while Uganda came second with four points. DR Congo squeezed through to the knockout phase as one of the best third teams.
Madagascar shocked tournament favorites Nigeria to finish top of Group B with seven points. The Super Eagles finished in second with six points. Guinea qualified as a third best team from the same group.
Algerians topped group C with the maximum nine points while Senegal came second with six points.
Morocco finished with nine points at top of Group D. The Atlas Lions were joined by Ivory Coast who came second and South Africa who squeezed through as one of the third-best teams.
Mali won Group E after beating Angola 1-0, and Tunisia claimed second after a goalless draw against Mauritania.
Ghana won group F after defeating Guinea-Bissau 2-0, with holders Cameroon taking second with a goalless draw against Benin. Benin qualified as one of the best third teams.
Angola, Burundi, Guinea-Bissau, Kenya, Mauritania, Namibia, Tanzania and Zimbabwe are the teams that crashed out.
Action will resume on Friday, 5 July when the first two games of the round of 16 are played. Two games will be played on the 6th, 7th and 8th to determine the eight quarter finalists.
Friday, July 5
Morocco vs. Benin, 7pm
Uganda vs. Senegal, 10pm
Saturday, July 6
Nigeria vs. Cameroon, 7pm
Egypt vs. South Africa, 10pm
Sunday, July 7
Madagascar vs. DR Congo, 7pm
Algeria vs. Guinea, 10pm
Monday, July 8
Mali vs. Ivory Coast, 7pm
Ghana vs. Tunisia, 10pm